診療科・部門

臨床研究センター 先進医療研究開発部 業績

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Department of Biomedical Research and Innovation


プレスリリース

 脳型ドレブリンを指標としたヒトiPS細胞由来神経細胞のシナプス成熟評価法の開発とシナプス形成過程の解明

英文業績

①原著論文

Nishimoto K, Ozaki T, Kidani T, Nakajima S, Kanemura Y, Yamazaki H, Fujinaka T: Flow Diverter Stenting for Symptomatic Intracranial Internal Carotid Artery Aneurysms: Clinical Outcomes and Factors for Symptom Improvement. Neurol Med Chir (Tokyo). 63:343-349, 2023

Fukusumi H, Togo K, Beck G, Shofuda T, Kanematsu D, Yamamoto A, Sumida M, Baba K, Mochizuki H, Kanemura Y: Human induced pluripotent stem cell line (ONHi001-A) generated from a patient with infantile neuroaxonal dystrophy having PLA2G6 c.517C > T (p.Q173X) and c.1634A > G (p.K545R) compound heterozygous mutations. Stem Cell Res 69:103122, 2023

Nakagawa T, Kijima N, Hasegawa K, Ikeda S, Yaga M, Wibowo T, Tachi T, Kuroda H, Hirayama R, Okita Y, Kinoshita M, Kagawa N, Kanemura Y, Hosen N, Kishima H: Identification of glioblastoma-specific antigens expressed in patient-derived tumor cells as candidate targets for chimeric antigen receptor T cell therapy. Neurooncol Adv 5:vdac177, 2022

Nakamura Y, Inoue A, Nishikawa M, Ohnishi T, Yano H, Kanemura Y, Ohtsuka Y, Ozaki S, Kusakabe K, Suehiro S, Yamashita D, Shigekawa S, Watanabe H, Kitazawa R, Tanaka J, Kunieda T: Quantitative measurement of peritumoral concentrations of glutamate, N-acetyl aspartate, and lactate on magnetic resonance spectroscopy predicts glioblastoma-related refractory epilepsy. Acta Neurochir (Wien) 164:3253-3266, 2022

Sanada T, Yamamoto S, Sakai M, Umehara T, Sato H, Saito M, Mitsui N, Hiroshima S, Anei R, Kanemura Y, Tanino M, Nakanishi K, Kishima H, Kinoshita M: Correlation of T1- to T2-weighted signal intensity ratio with T1- and T2-relaxation time and IDH mutation status in glioma. Sci Rep 12:18801, 2022

Yamazaki H, Fujinaka T, Ozaki T, Kidani T, Nishimoto K, Taki K, Nishizawa N, Murakami K, Kanemura Y, Nakajima S: Staged treatment for ruptured wide-neck intracranial aneurysm with intentional partial coiling in the acute phase followed by definitive treatment. Surg Neurol Int 13(322):1-7, 2022

Okada M, Kawagoe Y, Takasugi T, Nozumi M, Ito Y, Fukusumi H, Kanemura Y, Fujii Y, Igarashi M. JNK1‑Dependent Phosphorylation of GAP‑43 Serine 142 is a Novel Molecular Marker for Axonal Growth. Neurochem Res 47(9):2668-2682, 2022

Yamamoto T, Sato Y, Yasuda S, Shikamura M, Tamura T, Takenaka C, Takasu N, Nomura M, Dohi H, Takahashi M, Mandai M, Kanemura Y, Nakamura M, Okano H, Kawamata S: Correlation Between Genetic Abnormalities in Induced Pluripotent Stem Cell-Derivatives and Abnormal Tissue Formation in Tumorigenicity Tests. Stem Cells Transl Med 11(5):527-538, 2022

Ozaki T, Fujinaka T, Kidani T, Nishimoto K, Yamazaki H, Sawada H, Taki K, Kanemura Y, Nakajima S. Coil Embolization of Unruptured Cerebral Aneurysms Using Stents in Small Arteries Less Than 2 mm in Diameter. Neurosurgery 90(5):538-546, 2022

Matsuda K, Kokubo Y, Kanemura Y, Kanoto M, Sonoda Y: Preoperative Apparent Diffusion Coefficient of Peritumoral Lesion Associate with Recurrence in Patients with Glioblastoma. Neurol Med Chir (Tokyo) 62:28-34, 2022

Togo K, Fukusumi H, Shofuda T, Ohnishi H, Yamazaki H, Hayashi MK, Kawasaki N, Takei N, Nakazawa T, Saito Y, Baba K, Hashimoto H, Sekino Y, Shirao T, Mochizuki H, Kanemura Y: Postsynaptic structure formation of human iPS cell-derived neurons takes longer than presynaptic formation during neural differentiation in vitro. Mol Brain 14:149, 2021

Makino Y, Arakawa Y, Yoshioka E, Shofuda T, Minamiguchi S, Kawauchi T, Tanji M, Kanematsu D, Nonaka M, Okita Y, Kodama Y, Mano M, Hirose T, Mineharu Y, Miyamoto S, Kanemura Y: Infrequent RAS mutation is not associated with specific histological phenotype in gliomas. BMC Cancer 21:1025, 2021

Sugai K, Sumida M, Shofuda T, Yamaguchi R, Tamura T, Kohzuki T, Abe T, Shibata R, Kamata Y, Ito S, Okubo T, Tsuji O, Nori S, Nagoshi N, Yamanaka S, Kawamata S, Kanemura Y, Nakamura M, Okano H: First-in-human clinical trial of transplantation of iPSC-derived NS/PCs in subacute complete spinal cord injury: Study protocol. Regen Ther 18:321-333, 2021

Takami H, Satomi K, Fukuoka K, Fukushima S, Matsushita Y, Yamasaki K, Nakamura T, Tanaka S, Mukasa A, Saito N, Suzuki T, Yanagisawa T, Nakamura H, Sugiyama K, Tamura K, Maehara T, Nakada M, Nonaka M, Asai A, Yokogami K, Takeshima H, Iuchi T, Kanemura Y, Kobayashi K, Nagane M, Kurozumi K, Yoshimoto K, Matsuda M, Matsumura A, Hirose Y, Tokuyama T, Kumabe T, Narita Y, Shibui S, Nakazato Y, Nishikawa R, Matsutani M, Ichimura K: Low tumor cell content predicts favorable prognosis in germinoma patients. Neurooncol Adv 3:vdab110, 2021

Nakajo K, Uda T, Kawashima T, Terakawa Y, Ishibashi K, Tsuyuguchi N, Tanoue Y, Nagahama A, Uda H, Koh S, Sasaki T, Ohata K, Kanemura Y, Goto T: Maximum 11C-methionine PET uptake as a prognostic imaging biomarker for newly diagnosed and untreated astrocytic glioma. Sci Rep 12:546, 2022

Yamamoto S, Sanada T, Sakai M, Arisawa A, Kagawa N, Shimosegawa E, Nakanishi K, Kanemura Y, Kinoshita M, Kishima H: Prediction and Visualization of Non-Enhancing Tumor in Glioblastoma via T1w/T2w-Ratio Map. Brain Sci 12:99, 2022

Kinoshita M, Uchikoshi M, Tateishi S, Miyazaki S, Sakai M, Ozaki T, Asai K, Fujita Y, Matsuhashi T, Kanemura Y, Shimosegawa E, Hatazawa J, Nakatsuka SI, Kishima H, Nakanishi K: Magnetic Resonance Relaxometry for Tumor Cell Density Imaging for Glioma: An Exploratory Study via 11C-Methionine PET and Its Validation via Stereotactic Tissue Sampling. Cancers (Basel) 13:4067, 2021

Fujimoto K, Arita H, Satomi K, Yamasaki K, Matsushita Y, Nakamura T, Miyakita Y, Umehara T, Kobayashi K, Tamura K, Tanaka S, Higuchi F, Okita Y, Kanemura Y, Fukai J, Sakamoto D, Uda T, Machida R, Kuchiba A, Maehara T, Nagane M, Nishikawa R, Suzuki H, Shibuya M, Komori T, Narita Y, Ichimura K: TERT promoter mutation status is necessary and sufficient to diagnose IDH-wildtype diffuse astrocytic glioma with molecular features of glioblastoma. Acta Neuropathol 142:323-338, 2021

Makino Y, Arakawa Y, Yoshioka E, Shofuda T, Kawauchi T, Terada Y, Tanji M, Kanematsu D, Mineharu Y, Miyamoto S, Kanemura Y: Prognostic stratification for IDH-wild-type lower-grade astrocytoma by Sanger sequencing and copy-number alteration analysis with MLPA. Sci Rep 11:14408, 2021

Inoue A, Nishikawa M, Ohnishi T, Yano H, Kanemura Y, Ohtsuka Y, Ozaki S, Nakamura Y, Matsumoto S, Suehiro S, Yamashita D, Shigekawa S, Watanabe H, Kitazawa R, Tanaka J, Kunieda T: Prediction of glioma stem-like cell infiltration in the non-contrast-enhancing area by quantitative measurement of lactate on magnetic resonance spectroscopy in glioblastoma. World Neurosurg 153:e76-e95, 2021

Nishikawa M, Inoue A, Ohnishi T, Yano H, Ozaki S, Kanemura Y, Suehiro S, Ohtsuka Y, Kohno S, Ohue S, Shigekawa S, Watanabe H, Kitazawa R, Tanaka J, Kunieda T: Hypoxia-induced phenotypic transition from highly invasive to less invasive tumors in glioma stem-like cells: Significance of CD44 and osteopontin as therapeutic targets in glioblastoma. Transl Oncol 14:101137, 2021

Anami S, Fukai J, Hama M, Awaya A, Inagaki T, Chiba T, Noda Y, Kanemura Y, Nakao N, Sonomura T: Brainstem Infiltration Predicts Survival in Patients With High-grade Gliomas Treated With Chemoradiotherapy. Anticancer Res 41:2583-2589, 2021

Okada M, Kawagoe Y, Sato Y, Nozumi M, Ishikawa Y, Tamada A, Yamazaki H, Sekino Y, Kanemura Y, Shinmyo Y, Kawasaki H, Kaneko N, Sawamoto K, Fujii Y, Igarashi M: Phosphorylation of GAP-43 T172 is a molecular marker of growing axons in a wide range of mammals including primates. Mol Brain 14:66, 2021

Miyahara H, Natsumeda M, Kanemura Y, Yamasaki K, Riku Y, Akagi A, Oohashi W, Shofuda T, Yoshioka E, Sato Y, Taga T, Naruke Y, Ando R, Hasegawa D, Yoshida M, Sakaida T, Okada N, Watanabe H, Ozeki M, Arakawa Y, Yoshimura J, Fujii Y, Suenobu S, Ihara K, Hara J, Kakita A, Yoshida M, Iwasaki Y: Topoisomerase IIβ immunoreactivity (IR) co-localizes with neuronal marker-IR but not glial fibrillary acidic protein-IR in GLI3-positive medulloblastomas: an immunohistochemical analysis of 124 medulloblastomas from the Japan Children's Cancer Group. Brain Tumor Pathol 38:109-121, 2021

Takahashi S, Takahashi M, Kinoshita M, Miyake M, Kawaguchi R, Shinojima N, Mukasa A, Saito K, Nagane M, Otani R, Higuchi F, Tanaka S, Hata N, Tamura K, Tateishi K, Nishikawa R, Arita H, Nonaka M, Uda T, Fukai J, Okita Y, Tsuyuguchi N, Kanemura Y, Kobayashi K, Sese J, Ichimura K, Narita Y, Hamamoto R: Fine- Tuning Approach for Segmentation of Gliomas in Brain Magnetic Resonance Images with a Machine Learning Method to Normalize Image Differences among Facilities. Cancers (Basel). 13:1415, 2021

Ito N, Riyadh MA, Ahmad SAI, Hattori S, Kanemura Y, Kiyonari H, Abe T, Furuta Y, Shinmyo Y, Kaneko N, Hirota Y, Lupo G, Hatakeyama J, Abdulhaleem M FA, Anam MB, Yamaguchi M, Takeo T, Takebayashi H, Takebayashi M, Oike Y, Nakagata N, Shimamura K, Holtzman MJ, Takahashi Y, Guillemot F, Miyakawa T, Sawamoto K, Ohta K: Dysfunction of the proteoglycan Tsukushi causes hydrocephalus through altered neurogenesis in the subventricular zone in mice. Sci Transl Med 13:eaay7896, 2021

Nakajo K, Uda T, Kawashima T, Terakawa Y, Ishibashi K, Tsuyuguchi N, Tanoue Y, Nagahama A, Uda H, Koh S, Sasaki T, Ohata K, Kanemura Y, Goto T: Diagnostic Performance of [11C]Methionine Positron Emission Tomography in Newly Diagnosed and Untreated Glioma Based on the Revised World Health Organization 2016 Classification. World Neurosurg S1878-8750:00033-4, 2021

Kinoshita M, Arita H, Takahashi M, Uda T, Fukai J, Ishibashi K, Kijima N, Hirayama R, Sakai M, Arisawa A, Takahashi H, Nakanishi K, Kagawa N, Ichimura K, Kanemura Y, Narita Y, Kishima H: Impact of Inversion Time for FLAIR Acquisition on the T2-FLAIR Mismatch Detectability for IDH-Mutant, Non-CODEL Astrocytomas. Front Oncol 10:596448, 2021

Nishikawa M, Inoue A, Ohnishi T, Yano H, Kanemura Y, Kohno S, Ohue S, Ozaki S, Matsumoto S, Suehiro S, Nakamura Y, Shigekawa S, Watanabe H, Kitazawa R, Tanaka J, Kunieda T: CD44 expression in the tumor periphery predicts the responsiveness to bevacizumab in the treatment of recurrent glioblastoma. Cancer Med 10:2013-2025, 2021

Fukusumi H, Togo K, Sumida M, Nakamori M, Obika S, Baba K, Shofuda T, Ito D, Okano H, Mochizuki H, Kanemura Y: Alpha-synuclein dynamics in induced pluripotent stem cell-derived dopaminergic neurons from a Parkinson's disease patient (PARK4) with SNCA triplication. FEBS Open Bio 11: 354-366, 2021

Itai T, Miyatake S, Taguri M, Nozaki F, Ohta M, Osaka H, Morimoto M, Tandou T, Nohara F, Takami Y, Yoshioka F, Shimokawa S, Okuno-Yuguchi J, Motobayashi M, Takei Y, Fukuyama T, Kumada S, Miyata Y, Ogawa C, Maki Y, Togashi N, Ishikura T, Kinoshita M, Mitani Y, Kanemura Y, Omi T, Ando N, Hattori A, Saitoh S, Kitai Y, Hirai S, Arai H, Ishida F, Taniguchi H, Kitabatake Y, Ozono K, Nabatame S, Smigiel R, Kato M, Tanda K, Saito Y, Ishiyama A, Noguchi Y, Miura M, Nakano T, Hirano K, Honda R, Kuki I, Takanashi JI, Takeuchi A, Fukasawa T, Seiwa C, Harada A, Yachi Y, Higashiyama H, Terashima H, Kumagai T, Hada S, Abe Y, Miyagi E, Uchiyama Y, Fujita A, Imagawa E, Azuma Y, Hamanaka K, Koshimizu E, Mitsuhashi S, Mizuguchi T, Takata A, Miyake N, Tsurusaki Y, Doi H, Nakashima M, Saitsu H, Matsumoto N: Prenatal clinical manifestations in individuals with COL4A1/2 variants. J Med Genet 58:505-513, 2021

Kinoshita M, Uchikoshi M, Sakai M, Kanemura Y, Kishima H, Nakanishi K: T2-FLAIR Mismatch Sign Is Caused by Long T1 and T2 of IDH-mutant, 1p19q Non-codeleted Astrocytoma. Magn Reson Med Sci 20:119-123, 2021

Achiha T, Kijima N, Kodama Y, Kagawa N, Kinoshita M, Fujimoto Y, Nonaka M, Fukai J, Inoue A, Nishida N, Yamanaka T, Harada A, Mori K, Tsuyuguchi N, Uda T, Ishibashi K, Tomogane Y, Sakamoto D, Shofuda T, Yoshioka E, Kanematsu D, Mano M, Luu B, Taylor MD, Kanemura Y, Kishima H: Activated leukocyte cell adhesion molecule expression correlates with the WNT subgroup in medulloblastoma and is involved in regulating tumor cell proliferation and invasion. PLoS One 15:e0243272, 2020

Arita H, Matsushita Y, Machida R, Yamasaki K, Hata N, Ohno M, Yamaguchi S, Sasayama T, Tanaka S, Higuchi F, Iuchi T, Saito K, Kanamori M, Matsuda KI, Miyake Y, Tamura K, Tamai S, Nakamura T, Uda T, Okita Y, Fukai J, Sakamoto D, Hattori Y, Pareira ES, Hatae R, Ishi Y, Miyakita Y, Tanaka K, Takayanagi S, Otani R, Sakaida T, Kobayashi K, Saito R, Kurozumi K, Shofuda T, Nonaka M, Suzuki H, Shibuya M, Komori T, Sasaki H, Mizoguchi M, Kishima H, Nakada M, Sonoda Y, Tominaga T, Nagane M, Nishikawa R, Kanemura Y, Kuchiba A, Narita Y, Ichimura K: TERT promoter mutation confers favorable prognosis regardless of 1p/19q status in adult diffuse gliomas with IDH1/2 mutations. Acta Neuropathol Commun 8:201, 2020

Kikuchi Z, Shibahara I, Yamaki T, Yoshioka E, Shofuda T, Ohe R, Matsuda KI, Saito R, Kanamori M, Kanemura Y, Kumabe T, Tominaga T, Sonoda Y: TERT promoter mutation associated with multifocal phenotype and poor prognosis in patients with IDH wild-type glioblastoma. Neurooncol Adv 2:vdaa114, 2020

Okita Y, Shofuda T, Kanematsu D, Yoshioka E, Kodama Y, Mano M, Kinoshita M, Nonaka M, Fujinaka T, Kanemura Y: The association between 11 C-methionine uptake, IDH gene mutation, and MGMT promoter methylation in patients with grade II and III gliomasClin Radiol 75:622-628, 2020

Fukai J, Arita H, Umehara T, Yoshioka E, Shofuda T, Kanematsu D, Kodama Y, Mano M, Kinoshita M, Okita Y, Nonaka M, Uda T, Tsuyuguchi N, Sakamoto D, Uematsu Y, Nakao N, Mori K, Kanemura Y: Molecular characteristics and clinical outcomes of elderly patients with IDH-wildtype glioblastomas: comparative study of older and younger cases in Kansai Network cohort. Brain Tumor Pathol 37:50-59, 2020

Takami H, Fukushima S, Aoki K, Satomi K, Narumi K, Hama N, Matsushita Y, Fukuoka K, Yamasaki K, Nakamura T, Mukasa A, Saito N, Suzuki T, Yanagisawa T, Nakamura H, Sugiyama K, Tamura K, Maehara T, Nakada M, Nonaka M, Asai A, Yokogami K, Takeshima H, Iuchi T, Kanemura Y, Kobayashi K, Nagane M, Kurozumi K, Yoshimoto K, Matsuda M, Matsumura A, Hirose Y, Tokuyama T, Kumabe T, Ueki K, Narita Y, Shibui S, Totoki Y, Shibata T, Nakazato Y, Nishikawa R, Matsutani M, Ichimura K; Intracranial Germ Cell Tumor Genome Analysis Consortium (the iGCT Consortium): Intratumoural Immune Cell Landscape in Germinoma Reveals Multipotent Lineages and Exhibits Prognostic Significance. Neuropathol Appl Neurobiol 46:111-124, 2020

Yamaki T, Shibahra I, Matsuda KI, Kanemura Y, Konta T, Kanamori M, Yamakawa M, Tominaga T, Sonoda Y: Relationships between recurrence patterns and subventricular zone involvement or CD133 expression in glioblastoma. J Neurooncol 146:489-499, 2020

②症例報告

Mizushima M, Okamoto M, Yamaguchi S, Oki S, Motegi H, Sugiyama M, Manabe A, Shimizu A, Nishioka K, Hashimoto T, Hirato J, Kanemura Y, Fujimura M: Slow-growing WNT medulloblastoma with atypical magnetic resonance imaging findings: illustrative case. J Neurosurg Case Lessons 6: CASE23277, 2023

Okamoto N, Miya F, Tsunoda T, Kanemura Y, Saitoh S, Kato M, Yanagi K, Kaname T, Kosaki K: Four pedigrees with aminoacyl-tRNA synthetase abnormalities. Neurol Sci 43:2765-2774, 2022

Umehara T, Arita H, Miya F, Achiha T, Shofuda T, Yoshioka E, Kanematsu D, Nakagawa T, Kinoshita M, Kagawa N, Fujimoto Y, Hashimoto N, Kiyokawa H, Morii E, Tsunoda T, Kanemura Y, Kishima H: Revisiting the definition of glioma recurrence based on a phylogenetic investigation of primary and re-emerging tumor samples: a case report. Brain Tumor Pathol. 39:218-224, 2022

Takeuchi H, Takahashi Y, Tanigawa S, Okamoto T, Koddama Y, Shishido-Hara Y, Yoshioka E, Shofuda T, Kanemura Y, Konichi E, Hashimoto N:Genetic Alteration May Proceed with a Histological Change in Glioblastoma: A Report from Initially Diagnosed as Nontumor Lesion Cases.NMC Case Report Journal 9, 199-208, 2022

Izumi R, Takahashi H, Kanemura Y, Shofuda T, Yoshioka E, Narumi R, Matsubara S: Adducted thumb may not be mandatory for prenatal diagnosis of X-linked hydrocephalus in early second trimester. Taiwan J Obstet Gynecol 61:353-355, 2022

Nishizawa N, Ozaki T, Kidani T, Nakajima S, Kanemura Y, Nishimoto K, Yamazaki H, Mori K, Fujinaka T: Stent infection and pseudoaneurysm formation after carotid artery stent treated by excision and in situ reconstruction with polytetrafluoroethylene graft: A case report. Surg Neurol Int 13:24, 2022

Sawada H, Ozaki T, Nakajima S, Kidani T, Kanemura Y, Nishimoto K, Yamazaki H, Taki K, Fujinaka T: Tension pneumocephalus following cranioplasty with a titanium plate: a case report. J Int Med Res 50:3000605221076032, 2022

Sano K, Matsuda KI, Kawanami K, Kanemura Y, Ohe R, Sonoda Y: Malignant Progression of an IDH Mutant Brainstem Glioma in Adult. NMC Case Rep J 8:301-307, 2021

Okamoto N, Miya F, Kitai Y, Tsunoda T, Kato M, Saitoh S, Kanemura Y, Kosaki K: Homozygous ADCY5 mutation causes early-onset movement disorder with severe intellectual disability. Neurol Sci 42:2975-2978, 2021

Kijima N, Miuro S, Terada E, Nakagawa R, Tachi T, Murakami K, Okita Y, Kanemura Y, Nakajima S, Fujinaka T: Endovascular Treatment for Middle Cerebral Artery Aneurysms: Single-Center Experience and Review of Literatures. Journal of Neuroendovascular Therapy 15:213-219, 2021

Mitani Y, Fukuoka K, Mori M, Arakawa Y, Matsushita Y, Hibiya Y, Honda S, Kobayashi M, Tanami Y, Kanemura Y, Ichimura K, Nakazawa A, Kurihara J, Koh K: Clinical Aggressiveness of TP53-Wild Type Sonic Hedgehog Medulloblastoma With MYCN Amplification, Chromosome 17p Loss, and Chromothripsis. J Neuropathol Exp Neurol 80:205-207, 2021

Li Y, Nonaka M, Kanemura Y, Kodama Y, Mano M, Asai A: A case of medulloblastoma in a patient with fetal ventricular enlargement. Childs Nerv Sys 37:977-982, 2021

Miura S, Kijima N, Fujimori N, Nakagawa T, Nakagawa R, Tachi T, Okita Y, Kanemura Y, Nakajima S, Mano M, Kishima H, Ozawa K, Fujinaka T: Surgical Treatment of Brain Metastasis of Extramammary Paget's Disease: A Case Report. NMC Case Rep J 7:189-193, 2020

Aoki T, Kishimoto H, Hirato J, Kanemura Y, Mori M, Arakawa Y, Kurihara J, Oguma E, Koh K: A 21-month-old boy with vomiting, gait disturbance, and abnormal ocular alignment. Brain Pathol 30:425-426, 2020

Yotsumoto Y, Harada A, Tsugawa J, Ikura Y, Utsunomiya H, Miyatake S, Matsumoto N, Kanemura Y, Hashimoto-Tamaoki T: Infantile macrocephaly and multiple subcutaneous lipomas diagnosed with PTEN hamartoma tumor syndrome. Mol Clin Oncol 12:329-335, 2020

③総説

Kinoshita M, Kanemura Y, Narita Y, Kishima H: Reverse Engineering Glioma Radiomics to Conventional Neuroimaging. Neurol Med Chir (Tokyo). 61:505-514, 2021

Shofuda T, Kanemura Y: HDACs and MYC in medulloblastoma: how do HDAC inhibitors control MYC-amplified tumors? Neuro Oncol 23:173-174. 2021

④著書

Kinoshita M, Kanemura Y, Narita Y, Kishima H: Reverse Engineering Glioma Radiomics to Conventional Neuroimaging. Neurol Med Chir (Tokyo) 61:505-514, 2021

和文業績


①原著論文

寺田栄作, 木嶋教行, 村上皓紀, 中川僚太, 館 哲郎, 髙野浩司, 金村米博, 中島 伸, 藤中俊之:PipelineTM Flexを用いて再治療を行った血管内治療後再発内頚動脈瘤の5症例.脳卒中の外科 49:241-246, 2021

木嶋教行, 中川智義, 三浦慎平, 中川僚太, 舘 哲郎, 沖田典子, 金村米博, 中島 伸, 藤中俊之:重症くも膜下出血患者の治療戦略とその転帰.脳卒中の外科 49:98-102, 2021

館 哲郎,藤中俊之, 西本渓佑, 山崎弘輝, 村上皓紀, 高野浩司, 木谷知樹, 金村米博, 中島 伸:症候性内頸動脈瘤に対するPipeline Embolization Deviceの治療成績.脳神経外科ジャーナル29:864-869, 2020

②総説

金村米博:Medulloblastoma. Clinical Neuroscience 41:518-522, 2023

金村米博:小児脳腫瘍の分子診断.病理と臨床41:170-176, 2023

木下 学, 金村米博, 成田善孝, 貴島晴彦:神経膠腫の質的診断の進歩―画像と遺伝子―.脳神経外科ジャーナル31:4-10, 2022

金村米博:髄芽腫.脳神経外科 50:73-90, 2022

荒川芳輝,金村米博:外視鏡を用いた脳神経外科手術の現状と今後の展望 脳神経外科手術をより安全で正確な治療として進化させることが期待される(Q&A)  週刊日本医事新報 5046:51-52, 2021

金村米博:髄芽腫.脳神経外科 50:73-90, 2022

金村米博,永根基雄:分子分類時代における髄芽腫の治療法選択は? 新たな分類に基づいた、治療強度の最適化と有効な治療法の開発が望まれる(Q&A) 週刊日本医事新報 5033:51-53, 2020

金村米博:総論 悪性脳腫瘍の基礎から臨床の現状.Medical Science Digest 46:3-5, 2020

金村米博:NHOにおける臨床研究法の取り組みについて-認定臨床研究審査委員会の委員長の立場から-.医療74:283-287, 2020

③著書

金村米博:11章 先天奇形 §6 原因遺伝子が明らかになった脳神経外科手術の対象になる先天性疾患、§7 遺伝子探索の倫理的問題.脳神経外科学I第13版(原著 太田富雄、編集 松谷雅生・野崎和彦),P.1345-1375,株式会社金芳堂,2021

市村幸一,金村米博:13章 脳腫瘍 §1 総論 11 脳腫瘍遺伝子異常の検査体制.脳神経外科学II第13版(原著 太田富雄、編集 松谷雅生・野崎和彦),P.1568-1572,株式会社金芳堂,2021

金村米博:13章 脳腫瘍 §2 脳腫瘍各論 9 胎児性腫瘍 D.分子4型分類の概略.脳神経外科学II第13版(原著 太田富雄、編集 松谷雅生・野崎和彦),P.1748-1751,株式会社金芳堂,2021

金村米博:小児脳腫瘍における遺伝子異常.脳神経外科速報 2020年増刊 悪性脳腫瘍のすべて-Neuro-Oncologyの教科書-遺伝子診断時代の臨床リアルワールド(杉山一彦,橋本直哉 編集),P. 30-38, 株式会社メディカ出版,2020